The most ethical source of stem cells which happens to be the most abundant

Two decades of stem cell research

Stem cell research is probably the most exciting field in science to touch the skin care industry in a long time. At CALECIM® Professional, we’ve harnessed 20 years of stem cell research by our parent company CellResearchCorp and created a new and completely ground-breaking cosmeceutical.

To understand the science that makes CALECIM® Professional products unique, it’s necessary to understand more about the fascinating cells it comes from, how they communicate, and the possibilities they hold.

The Importance of Stem Cells

Stem cells are unique; they can differentiate into specialized cells or divide to produce more stem cells of their own type, they are responsible for healing, maintaining growth, and replacing the old cells in our skin. As we age, the numbers and activity of the stem cells in our body and skin slowly decrease. As they do, our skin gradually loses its ability to repair and restore itself, and hence, we start to see signs of aging.

The most ethical source of stem cells

CellResearchCorp obtains stem cells to produce CALECIM® Professional from the umbilical cord lining membrane of red deer. The umbilical cord lining membrane, in both humans and other mammals, is the most abundant source of Epithelial and Mesenchymal stem cells known to date. The numbers that can be harvested vastly exceeds any other source, including bone marrow and fat. The stem cells isolated from cord lining membrane are neonatal cells, and as such are much more potent and robust compared to their adult sourced counterparts.

One source, two types of stem cells 

In 2004, CellResearchCorp discovered Cord Lining Stem Cells and patented culture techniques to isolate both epithelial stem cells and mesenchymal stem cells from the cord lining membrane. These cells hold special interest as they govern the body’s ability to heal and regenerate.

Epithelial Stem Cells (EpSC) for skincare 

EpSC carry out the renewal of epithelial tissues. Epithelial tissue covers outer and inner surfaces of the body. In addition to the skin, it also lines the digestive and respiratory tracts. Within the skin, the innermost layer of the epidermis holds stem cells which continually create new cells to replace those that are old or damaged.

Mesenchymal Stem Cells (MSC) for skincare

MSCs play a major role in the body’s defense against injury and stress. They are able to differentiate into a variety of stem cell types, including bone, nerve, and fat cells. MSCs can also travel within the body to the location of a wound or injury to direct the healing response.

How Cells Talk To Each Other (Intercellular messages): All about growth factors and exosomes

Both EpSC and MSC communicate with each other, and other cell types, through secreted proteins called growth factors. These unique growth factors are encased in exosomes and trigger specific receptors on cell membranes, creating targeted responses. When new cell growth or protein synthesis happens in the skin, it’s a result of these growth factor messages being sent from stem cells to cells in the dermis and epidermis. We call these “youth-messages” or “power-proteins” as they essentially can tell your skin to act younger. This is basically what our patented active ingredient PTT-6® is. 

How do we obtain PTT-6® from stem cells

Stem cells are grown in a cultivating solution called Culture Medium, where they secrete growth factors, exosomes and proteins. Culture Medium which now contains all these proteins secreted by the Stem Cells is called PTT-6®. The conditioned media (PTT-6®) is collected, leaving the stem cells behind.

PTT-6® is essentially a power cell-growth medium that has been conditioned by epithelial and mesenchymal stem cells. This source of growth factors and exosomes is unique and patented. 

The best stem cell skincare for anti-aging 

Every CALECIM® Professional product contains an optimal concentration of PTT-6®, which works to restore and rejuvenate the skin. Applying PTT-6® to the skin has shown to speed up healing, dramatically improve the skin’s appearance, and effect structural changes in the skin over time. The result is the correction of various ageing symptoms such as loss of skin fullness, volume, and facial definition, as well as lines and wrinkles, pigmentation and loss of skin density and elasticity. With its powerful medium of “youth- messages”, CALECIM® Professional is able to show positive results in as little as two weeks. See the results yourself in these clinical trials.

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