Country Availability

Free shipping and country tax is absorbed in these countries
Singapore, United States*, United Kingdom
*State tax may apply in certain states in the US
Free shipping and taxes are charged in these countries
Albania, Andorra, Armenia, Austria, Belarus, Bosnia & Herzegovina, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Georgia, Germany, Gibraltar, Greece, Greenland, Guernsey, Hungary, Iceland, Ireland, Isle of Man, Jersey, Kosovo, Latvia, Liechtenstein, Lithuania, Malta, Monaco, Montenegro, North Macedonia, Norway, Poland, Portugal, Romania, San Marino, Serbia, Slovakia, Slovenia, Sweden, Turkey, Ukraine, Morocco
Delivery fees are charged in these countries
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For all other countries, please email us at customerservice@calecim.com

Delivery Information

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Delivery Time
Orders within USA
3 to 6 working days
Orders within UK
3 to 6 working days
Orders within Singapore*
2 working days
International Shipping
Up to 14 working days
 
 
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OUR INGREDIENTS

The future of beauty lies in scientifically advanced ingredients that are validated by clinical data and patient results. Find out more about the ingredients that make our formulations so powerful.

FEATURED INGREDIENTS

PTT-6®

PTT-6® harnesses the body’s natural mechanisms of regeneration. It contains over 3,000 proteins, including growth factors, cytokines, and exosomes that signal cells to regenerate.

Growth Factors

Naturally occurring proteins that are produced by cells in your body, such as skin cells, fat cells or stem cells. Their role is to stimulate growth, healing and regeneration in living tissues. Depending on its type and source, growth factors can boost collagen synthesis, prompt cells to produce components that improve skin firmness and elasticity, strengthen the skin barrier and repair and rejuvenate skin.

Exosomes

Found in all mammalian cells, exosomes are nano-sized extracellular vesicles that are released from cells . Exosomes contain proteins and growth factors that are important in helping one cell communicate with another to promote healing.

Stem Cells

Stem cells act as the repair system of the body due to their tremendous capacity for regeneration. Everyone has stem cells in their body but their numbers and quality drop with age.

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Albumin
A protein that maintains osmotic (water) pressure within the skin's cells. It is required for skin turgor, helping to maintain a plump and youthful complexion.
Allantoin
A highly effective moisturizer working to relieve irritation in the form of dry, rough and itchy skin.
Aloe Barbadensis
Taken from the Aloe plant, this expressed leaf juice is known for its soothing, healing and skin-calming properties. High in antioxidants, it reduces inflammation while hydrating the skin.
Alpha-Arbutin
Reduces Tyrosinase activity, the enzyme that controls the production of melanin, and allows for a more even skin tone. It reduces the appearance of age spots, acne scars and post-blemished skin.
Arisaema Amurense
A plant-derived skin conditioning agent that reduces the appearance of age spots and blemishes by accelerating the processing of unwanted tissue such as melanin.
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Butylresorcinol
A highly effective topical treatment which works to inhibit Tyrosinase, the enzyme that controls the production of melanin and can cause hyperpigmentation. 4-n-Butylresorcinol works to reduce this melanin production and distribution, acting as a skin lightening agent.
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Calmosensine
An anti-aging, calming and soothing conditioning agent that is known for its cooling and calming properties. It acts as a regulator for the senses to reduce sensitivity and improve skin comfort.
Camellia Sinensis Leaf extract
A Green Tea extract rich in bioactive compounds including catechins and L-theanine. it demonstrates antioxidant, anti-inflammatory and anti-microbial properties, working to reduce UV damage and skin redness.
Cucumis Sativus extract
Also known as Cucumber extract, Cucumis Sativus softens refreshes and revitalizes the skin, helping to reduce pore size and clarify the complexion.
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Epithelial Stem Cells
A type of stem cell that is central to tissue formation, wound repair and cell death. These stem cells are responsible for the covering of skin on your body and internal organs. Epithelial stem cells also play a role in hair follicle function. They are signal-receiving cells and receive cues to stimulate cell cycle to maintain skin and scalp health.
Exosomes
Found in all mammalian cells, exosomes are nano-sized extracellular vesicles that are released from cells . Exosomes contain proteins and growth factors that are important in helping one cell communicate with another to promote healing.
EXOSOME
PTT-6® harnesses the body’s natural mechanisms of regeneration.
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Fibronectins
One of the gkycoproteins in PTT-6® that helps repair skin and build collagen by providing the binding element required for these processes to take place. It strengthens, hydrates and protects skin cells.
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Glutathione
An antioxidant that improves hyperpigmentation by interrupting Tyrosinase, the enzyme that controls the production of melanin. It brightens the complexion for a more even skin tone.
Growth Factors
Naturally occurring proteins that are produced by cells in your body, such as skin cells, fat cells or stem cells. Their role is to stimulate growth, healing and regeneration in living tissues. Depending on its type and source, growth factors can boost collagen synthesis, prompt cells to produce components that improve skin firmness and elasticity, strengthen the skin barrier and repair and rejuvenate skin.
GROWTH FACTOR
It contains over 3,000 proteins, including growth factors, cytokines, and exosomes that signal cells to regenerate.
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Hesperidin and other lipopeptides
Naturally found in citrus fruits, this complex of peptides increases micro-circulation of the blood, decreasing dark circles and puffiness.
Hyaluronic Acid
A substance that is naturally found in skin and is capable of holding 1,000 times its weight in water. It increases the moisture content of the skin by acting as a natural hydrator. Hyaluronic Acid helps the skin to stretch and flex, eliminating the appearance of fine lines and wrinkles. It also has been proven to help repair damage and reduce scarring.
Hydrolyzed Sodium Hyaluronate
A form of Hyaluronic Acid that has gone through the process of hydrolysis. This means that Hydrolyzed Sodium Hyaluronate has had water added to it, so it now has a lower molecular weight and can penetrate the skin more easily. This results in increased penetration to the skin's surface and deeper layers.
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Interleukin-10
A unique signally growth factor that produces anti-inflammatory properties and promotes healing.
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Lactic Acid
Acts as an exfoliant for the skin, it works by removing the top layer of dead skin cells, and helping increase cellular turnover. This allows for softened skin, retained moisture and a renewed radiance.
Lecithin
Packed with antioxidants, Lecithin is derived from plants including soy, rapeseed and sunflower. It works to replenish and soften the skin, boost hydration and lock in moisture while reducing skin inflammation.
Linolenic Acid
A naturally occurring fatty acid that hydrates, soothes and conditions the skin while reducing inflammation and irritation. It limits the appearance of fine lines and hyperpigmentation by accelerating the removal of melanin from the top layer of the skin.
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Matrikines
Peptides naturally found in the extracellular matrix of your skin that help degenerate blood-originated pigments responsible for dark circles.
Mesenchymal Cells
A type of stem cell that is responsible for the formation of many body parts, including the deeper layers of skin. Its function is to promote tissue repair by releasing growth factors and cytokines which help recruit cells to the injury site.
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Palmitoyl
Stimulates the production of collagen, working to firm the skin and reduce the appearance of fine lines and wrinkles.
Paullinia Cupana Seed Extract
A Guarana fruit extract, native to the Amazon, that contains caffeine which stimulates and revitalizes skin. It also protects the skin from free radical damage that can speed up the aging process.
Plant and Fruit Oil Extracts
These include Jojoba Seed Wax, Olive Oil, Sunflower Seed Oil, Lemon Fruit Extract, Passionfruit Extract and Pineapple Extract, each of which contain antioxidant properties to soothe, nourish and hydrate the skin, and prevent damage from free radicals.
PTT-6®
PTT-6® harnesses the body's natural mechanisms of regeneration. It contains over 3,000 proteins, including growth factors, cytokines and exosomes that signal cells to regenerate.
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Saccharide Isomerate
Soothes and hydrates for soft, plump skin. It does this by influencing proteins found in the outer layers of the skin, working to strengthen the skin's barrier to make it less susceptible to environmental aggressors.
Sodium Ascorbyl Phosphate
A water-soluble and stable derivative of Vitamin C. Packed with antioxidants, Sodium Ascorbyl Phosphate reduces skin discoloration while brightening the complexion, smoothening fine lines and firming the skin. It has additional antimicrobial properties to reduce skin breakouts while building up the skin's resistance to inflammatory stimulants.
Sodium Hyaluronate
A salt form of Hyaluronic Acid which is bioavailable, meaning it is more readily absorbed into the skin. It provides deep hydration while working to maintain the skin's microbiome.
Soluble Collagen
One of the most hydrating ingredients to be used on the surface of the skin. When applied, it produces a water-rich film which allows for retained moisture and hydration. It brings shape, strength and structure to the skin's cells.
Stem Cells
Stem cells act as the repair system of the body due to their tremendous capacity for regeneration. Everyone has stem cells in their body but their numbers and quality drop with age.
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Tocopherol
An antioxidant and the active form of Vitamin E. It naturally occurs in the body but can become depleted from environmental aggressors. Tocopherol provides deep replenishment and reduces inflammation, while protecting the skin membrane from free radicals.
Tranexamic Acid
Comes from amino acid lysine, which is known for its benefits in treating melasma, hyperpigmentation and skin discoloration. It works by interrupting the pathway that would normally lead to the deposit of melanin and resulting discoloration. It inhibits the release of inflammatory mediators involved in melanin production.
Tyrosinase
A naturally occurring enzyme found in our skin cells. It triggers the production of melanin which effects the skin's pigmentation process.
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Vitis Vinifera Seed Oil
Also known as Grape Seed oil, it is derived from the seeds of grapes. Packed with antioxidants, it protects the skin from environmental aggressors and free radical damage.
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