Treat lax, thinning and aging skin with stem cell exosomes

The skin is the body’s largest organ – and one of the most fascinating. On a daily basis, it is exposed to sunlight, pollution, dirt, and low humidity, all of which can lead to skin that’s dry, rough, wrinkled, lax, and pigmented.

However, the most consistent negative impact on the skin comes from ageing. Young skin can renew itself efficiently, with a complete skin renewal cycle of about 28 days. But ageing slows down this process, resulting in skin that grows progressively dull-looking and lax. Consistent renewal is essential for skin to maintain its shine and elasticity, and it loses these qualities when old and dry cells accumulate on the surface of skin, resulting in a crepey texture, rigid and dry surface, as well as pigmentation.

We will explain why a daily application of CALECIM® Professional Multi-Action Cream can help restore and maintain smooth, healthy, and youthful-looking skin.

Stem cells and the growth factors and exosomes they produce 

The role of stem cells in skin turnover and regeneration is quite well understood. Stem cells are the building blocks of the entire body as well as an essential repair system. Like with other body parts,  they help your skin:

  • Heal
  • Restore
  • Regenerate

Stem cells are able to do this by sending out messages ‘instructing’ cells to behave in certain ways to repair and regenerate.

What are some of these instructions? They include messages in the form of growth factors and exosomes that steer cells towards each other, especially when there is a wound to be closed. Others include signals for cells to proliferate at every level, at the epidermis and dermis. And also for old skin cells to be shed, so that fresh new skin cells can rise to the surface.

At CALECIM® Professional, we like to think of these signals as “Youth Messages” because they help restore skin function, ensuring that there is sufficient cell production, that there is a regular skin cycle so that old cells can shed, and that our skin can tackle the daily ravages of the environment by healing efficiently.

What aging does to your skin

As you age, however, stem cells are adversely affected in two ways:

  • Stem cells decline in number resulting in decreased cell signals
  • The signals that old stem cells send out are also less powerful

This can affect your skin both on the surface (the epidermis) and down in the deeper layers (the dermis).

Deep down in the thicker dermal layer, the structural support for the entire skin system is compromised with decreased stem cell signalling. This leads to a declining production of:

  • Collagen, which provides strength and shape to the skin. Skin loses volume.
  • Elastin, which provides suppleness and resiliency to the skin. Skin becomes lax, droops and forms deep wrinkles.
  • Hyaluronic acid (HA), which helps hydrate the skin to keep it full and inflated. Skin becomes dry and thin, and loses its youthful radiance

Decreased stem cell signalling also means that a healthy skin cycle is compromised. What used to be a 28 day cycle in youthful skin is now extended to 40 days or more. When this happens, old skin cells accumulate on the surface, leading to a dry and crepey texture as well as pigmentation.

Multi-Action Cream: daily boost of stem cell signals

CALECIM® Professional Multi-Action Cream is a corrective treatment cream that can be applied under your daily moisturizer. Its proprietary technology is PTT-6® , a mix of growth factors and exosomes derived from ethically sourced stem cells. These signalling cells are the “Youth Messages” that can help rejuvenate skin, prompting skin to act in a more youthful manner.

It effectively works to:

  • Improve skin contour
  • Increase skin fullness
  • Volumize thin skin
  • Smoothen deep facial wrinkles and creases, such as nasolabial folds
  • Restore uneven skin tone and color

Multi-Action Cream is able to do this because of the unique blend of cell signals, popularly known as exosomes, derived from mesenchymal and epithelial stem cells extracted from cord lining. Mesenchymal stem cells are responsible for the development of the dermal layer of skin; proteins derived from mesenchymal stem cells are thus able to communicate with dermal tissue to increase glycoprotein production. This leads to firmer skin that is resilient and elastic.

Epithelial stem cells which are responsible for the development of the epidermis produce proteins that can communicate with the epidermal layer, encouraging a healthy cell production and cell shedding cycle.

The result is skin that is rejuvenated at many levels, with a visible difference in just two weeks.

What is in PTT-6®  that makes it the most potent source of exosomes and growth factors? 

It is hard to decipher what exactly is found in the protein mix produced by cord lining stem cells, as this blend is truly ‘created by nature’. Scientists are, however, able to determine the presence of the following ingredients:

  • Collagen for shaping and strengthening the skin
  • Hyaluronic acid for plumping the skin up for more volume
  • Albumin for skin tightening and firming
  • Fibronectin to support collagen’s shaping and strengthening properties

     And of course,

  • Peptides (building blocks of proteins), growth factors and exosome that are the “Youth Messages” of the stem cells

Dermatologists recommend the Multi-Action Cream as a daily corrective treatment, to be used AM and PM, and before application of your regular moisturizer or CALECIM®  Professional Restorative Hydration Cream if you have dry skin. The Multi-Action Cream will suffice as a moisturizer for those with oily and combination skin. Many report visible difference in 2-4 weeks of use, with optimal results in 90 days.

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