






Skincare's Favorite Hydrator
Hyaluronic Acid
Hyaluronic Acid (HA) is naturally produced by our body. It is also found in many serums and creams because of its ability to hold and retain water, with visible benefits in plumping and hydrating the skin.
Naturally Secreted By
Cord Lining Stem Cells
Hyaluronic Acid is also naturally secreted by our patented source of stem cells. Restorative Hydration Cream is the only moisturizing cream in the world that uses HA from Cord Lining Stem Cells.
Replenish from Within
The amount of naturally occurring Hyaluronic Acid in our body decreases as we get older. Cord Lining Conditioned Media has been shown in-vitro to encourage increase in HA production by skin cells.
83%
Increase in
HA production
Results from in-vitro tests using Cord Lining Conditioned Media
and skin fibroblasts
Immunohistochemistry staining for HA
In-vitro tests using human dermal fibroblasts
To compare effects of human dermal fibroblasts
with Cord Lining Conditioned Media
Using a series of optical density images
Showed that CLCM upregulated expression of HA by 83%

Accelerate the Skin Cycle for Healthier Skin
A regular cell turnover is essential for new skin cells to rise to the epidermis. Old skin cells that remain on the skin surface lose the ability to retain moisture, leading to dry, crepey skin.
This occurs in older skin types when the skin cell cycle is disrupted.
In-vitro tests reveal that Cord Lining extract is able to accelerate cell production in aged skin cells.
42%
Increase in
skin cell proliferation
Results from in-vitro tests using Cord Lining Conditioned Media
and skin fibroblasts
Evidence of Increased Epidermal Proliferation
In-vitro tests using aged skin keratinocytes
and fibroblasts reveal:
A significant increase in epidermal cell proliferation was observed
from Day 6 onwards after exposure to
Cord Lining Conditioned Media.

Restoring the skin's epidermal cell cycle is important so that fresh, new cells can rise to the surface. The visible effect is a natural radiance and a 'glow from within'.
Created by Scientists

“Patients see and feel a difference in their skin: Smoother texture. Increased hydration from within. Overall improved skin tone.”
TRUSTED BY
Adrian Baker
Aesthetic Nurse,
Founder of Lumiere MediSpa
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The 14-day difference with
Restorative Hydration Cream
Clinically Validated
by Patients
Our active ingredient, Rejuvenating Conditioned Media, is not just studied and vigorously tested in the lab.
Its results on real patients speak for themselves.
How to Use
- Cleanse and tone skin
- Apply a small amount to all facial zones, extending past the jawline to the neck. Gently smooth the cream in.
- Use on its own, or above corrective serums or creams like Multi-Action Cream. Use AM and PM.
Use Together
Powerful Alone.
Transformative Together.
Restorative Hydration Cream +
Multi-Action Cream


Try the power duo now in starter sizes:


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MyCALECIM®
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More Questions
Which do I choose: Multi-Action Cream or Restorative Hydration Cream?
Which do I choose: Multi-Action Cream or Restorative Hydration Cream?
Multi-Action Cream is designed for patients who are looking for a powerful anti-aging corrective treatment. It targets significant signs of aging such as skin laxity, deep wrinkles and folds, and loss of skin density.
Restorative Hydration Cream is for all skin types that will benefit from deep hydration. It restores radiance to dehydrated skin, smoothing out fine line and shadows.
These two products can be used together. With the Multi-Action Cream being applied before the Restorative Hydration Cream.
Why does my current jar of Restorative Hydration Cream look and smell different from the last one?
Why does my current jar of Restorative Hydration Cream look and smell different from the last one?
The extract derived from each batch of Cord Lining is slightly different. This results in slight differences in color and smell in the end product because of the high concentration of active ingredient used.
When can I start seeing results from the Restorative Hydration Cream?
When can I start seeing results from the Restorative Hydration Cream?
When used as a daily moisturizer or corrective treatment, Restorative Hydration Cream supplies the skin nutrients that aids and boosts the restoration of your skin’s renewal cycle back to 28 days. This process is known as the skin-cycle reset and may take two to four weeks for results to take effect. Optimal results can usually be observed after 90 days.
Can I use CALECIM® Professional with types of Vitamin C, AHAs, BHAs and anti-oxidants?
How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?
Can I use CALECIM® Professional with types of Vitamin C, AHAs, BHAs and anti-oxidants?
How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?
CALECIM® Professional works well with most active ingredients commonly used in other skincare. Your skincare should be layered according to the viscosity of the product. Water-based products should be applied first (like toners, and watery serums), followed by gel-like textures. Light creams can be applied after, followed by heavier creams. For AM regimens, sunblock should be applied last.
Is this safe to use immediately after a skin procedure?
Is this safe to use immediately after a skin procedure?
It depends on how ablative your procedure was. All creams / serums / gels should only be applied to skin that has fully epithelized.
Can I use CALECIM® Professional products if I have acne?
Can I use CALECIM® Professional products if I have acne?
While the occasional pimple may be part of the natural process of skin renewal, you should avoid the use any CALECIM® Professional skincare if you have active acne. Your doctor or dermatologist will be able to ascertain whether you are a suitable candidate for the product.
Can I use CALECIM® Professional products if I am breast-feeding or pregnant?
Can I use CALECIM® Professional products if I am breast-feeding or pregnant?
Yes, CALECIM® Professional products are safe for those who are pregnant or breastfeeding. However, we highly recommend that you consult your obstetrician/gynaecologist before starting any new skincare routine.
Is CALECIM® Professional approved by the USFDA?
Is CALECIM® Professional approved by the USFDA?
Cosmetic products such as CALECIM® Professional do not require the approval of the USFDA to enter a market. The cosmetic industry is however regulated by the USFDA through its VCRP program. CALECIM® Professional and all its products are registered with the USFDA VCRP.
Active Ingredients
Active Ingredients
Cord Lining Conditioned Media (Stem cell derived Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid), Aloe Barbadensis Leaf Juice, Tocopherol, Potassium Lactate, Fatty Acids (Oleic Acid, Linoleic acid, Palmitic acid, Stearic acid), Gylceryl Stearate