Post-procedure treatment to enhance
skin’s restoration process

Professional Serum 1.5ml (Free Gift)

Produced in a
Stem Cell Lab


Trusted by


Skin's Healing Capacity Decreases with Age

Skin's Healing Capacity
Decreases with Age

Stem cell stimulation is responsible for repair and regeneration work in the body.

As we age, the numbers of stem cells in our body fall, accompanied by a decrease in their efficiency. This is why young children recover from wounds relatively quickly without scarring, while older people take longer to heal; scarring takes place as a result of imperfect healing.

Replenish Essential

The complex mix of proteins and cytokines secreted by Cord Lining Stem Cells works on damaged and aging skin by replenishing these essential cellular messages.

Stem CellSignals

Aid in suppressing pro-inflammatory cytokines

Encourage skin cells to renew

Activate cells to migrate towards skin damage

Help build up skin’s structural layers

These signals initiate many cellular events which may translate to decreased skin sensitivity and irritation, improved skin density, and increased resilience.

More on Our Science

Created by Scientists

Dr. Dan Kim

CALECIM® Professional serum has proven its value many times over as a great adjunct to post-operative laser skin care. Its efficacy is undeniable with its anti-inflammatory property and its ability to decrease swelling and erythema.”


Dr. Dan Kim

Plastic Surgeon,
Orange County, USA

See Clinical Observation by Dr. Kim
Dr. Cheryl Effron

“For over 35 years of offering laser treatment as part of my Aesthetic Practice, I have searched for the perfect laser recovery serum. I found it in CALECIM® Professional. It is the perfect post-laser procedure serum with an elegant vehicle that offers comfort for the repair process.”


Dr. Cheryl Effron

Cosmetic Dermatologist,
Orange County, USA

See Clinical Observation by Dr. Effron

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Before using Serum - Image 1 After using Serum - Image 1

12 week treatment of acne and acne scarring using topical treatments, microneedling and Professional Serum. Conducted by Adrian Baker of Lumiere MediSpa

Before using Serum - Image 2 After using Serum - Image 2

Plasma shower treatment with Professional Serum infusion.
Conducted by Dr B. Molina, Medikas

Before using Serum - Image 3 After using Serum - Image 3

Microneedling treatment with application of Professional Serum.
Conducted by L. Reynolds, Harley Street Skin

Before using Serum - Image 4 After using Serum - Image 4

4 sessions of Nano-fractional radio frequency treatment with application of Professional Serum, over 12 weeks. Conducted by Dr R. Pamela, CELV Clinic

Before using Serum - Image 5 After using Serum - Image 5

4 sessions of Nano-fractional radio frequency treatment with application of Professional Serum, over 12 weeks. Conducted by Dr R. Pamela, CELV Clinic

Side with no application of Serum Side with application of Serum

Split-face trial with Professional Serum applied on one side of face post ablative laser procedure. Conducted by Dr D Kim, Orange County Plastic Surgery

Serum Split Face Trial - Image 8

Professional Serum applied on right side post ablative laser procedure.
Conducted by Dr D Kim, Orange County Plastic Surgery

Enhanced recovery and optimized treatment results with Professional Serum

Clinically Validated
by Patients

Our active ingredient, Rejuvenating Conditioned Media, is not just studied and vigorously tested in the lab.

Its results on real patients speak for themselves.

Why is the Professional Serum pink?

Why is the Professional Serum pink?

The Professional Serum uses a pH indicator to monitor the state of its active growth factors and proteins. Because of its high concentration of biologically-derived active ingredient, it is important that the conditions remain optimal for these active factors to thrive. While a range of colors reflects that the acidity level is acceptable - from light/dark pink to orange - you should not use the product if it turns yellow or becomes cloudy.

How to Use

When Used After Clinical Procedures:

  • Apply to treatment area and press firmly into the skin with a gloved hand to ensure penetration. Use half to one full ampoule per treatment depending on area and degree of ablation.
  • Continued usage at home is recommended. Number of days of post-treatment application should be advised by your physician.

When Used at Home as a Skin Booster:

  • Ensure skin is clean and free of any oily residue. A mild skin exfoliation before application might improve absorption of the product.
  • Use one pipette-full of Serum for the whole face. Apply a few drops on each facial zone and press into the skin. One ampoule holds approximately 10 pipettes of Serum.
  • Can be used AM / PM. Apply your regular moisturizer / treatment creams such as Multi-Action Cream and / or Restorative Hydration Cream after.
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More Questions

Which product do I choose to use post-procedure: Professional Serum or Recovery Night Complex?

The Professional Serum is designed to be used after in-clinic procedures. It is light and easily absorbed into the skin with a pH that is designed to be gentle on sensitized skin.

The Recovery Night Complex can also be used on sensitized skin, but it is better applied at night because of its gel like texture that forms alight film over the skin to protect and hydrate it. This texture is also not conducive to the convenient application of sunblock or makeup which is why it is not recommended for use in the day.

As a night-time regimen on the day of the procedure, you can apply the Professional Serum followed by the Recovery Night Complex.

Why is the Professional Serum pink?

Professional Serum contains phenolsulfonphthalein (a pH indicator) which is reddish/dark pink. As each batch of protein mix may have slight differences in acidity or alkalinity, the color can range from light yellow/orange to light red/dark pink. This is within our acceptable range.

We use the pH indicator to monitor the state of the active ingredient. As it is derived from an organic source and is high in biological matter, it may be prone to bacteria contamination. The pH indicator uses the acidity level within the formula to assess the health of the active proteins and growth factors within.

It is recommended to keep CALECIM® Professional products in cool conditions, not exceeding 33°C or 91.4°F. Please discontinue usage of the product if the color appears to be different from the stated acceptable range and contact us at

Why is there a smell to the Professional Serum?

The Professional Serum is fragrance-free. The smell comes from the high concentration of active ingredient, mainly Cord Lining extract, in the formulation. The smell disappears soon after application and most users don’t notice it after a few minutes.

Why does my ampoule of Professional Serum look and smell different from the last one?

The extract derived from each batch of Cord Lining is slightly different. This results in slight differences in color and smell in the end product because of the high concentration of active ingredient used.

When can I start seeing results from the Professional Serum?

When Professional Serum is used after in-clinic procedures, the calming and soothing effect is usually quite rapid with patients experiencing some amounts of decreased redness, swelling and discomfort within 15 minutes of application.

Can I use CALECIM® Professional with types of Vitamin C, AHAs, BHAs and anti-oxidants?
How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?

CALECIM® Professional works well with most active ingredients commonly used in other skincare. Your skincare should be layered according to the viscosity of the product. Water-based products should be applied first (like toners, and watery serums), followed by gel-like textures. Light creams can be applied after, followed by heavier creams. For AM regimens, sunblock should be applied last.

Is this safe to use immediately after a skin procedure?

It depends on how ablative your procedure was. All creams / serums / gels should only be applied to skin that has fully epithelized.

Can I use CALECIM® Professional products if I have acne?

While the occasional pimple may be part of the natural process of skin renewal, you should avoid the use any CALECIM® Professional skincare if you have active acne. Your doctor or dermatologist will be able to ascertain whether you are a suitable candidate for the product.

Can I use CALECIM® Professional products if I am breast-feeding or pregnant?

Yes, CALECIM® Professional products are safe for those who are pregnant or breastfeeding. However, we highly recommend that you consult your obstetrician/gynaecologist before starting any new skincare routine.

Is CALECIM® Professional approved by the USFDA?

Cosmetic products such as CALECIM® Professional do not require the approval of the USFDA to enter a market. The cosmetic industry is however regulated by the USFDA through its VCRP program. CALECIM® Professional and all its products are registered with the USFDA VCRP.

Active Ingredients

Cord Lining Conditioned Media (Stem cell derived Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid)