Size Guide
Rings NECKLACES & PENDANTS BRACELETS
Size#1 CIRCUMFERENCE DIAMETER
HK US MM MM
5 - 43.3 13.8
6 3 44.3 14.1
Size#2 CIRCUMFERENCE DIAMETER
HK US MM MM
5 - 43.3 13.8
6 3 44.3 14.1
Size#3 CIRCUMFERENCE DIAMETER
HK US MM MM
5 - 43.3 13.8
6 3 44.3 14.1
Determine Your Ring Size

MEASURE YOUR RING SIZE WITH A PIECE OF PAPER

  1. Find a strip of paper that is at least 10cm long.
  2. Wrap it around your finger.
  3. Use a pen or maker to mark the point where the end meet.
  4. Lay the paper on the ruler and annotate the measurement in millimetre (mm).
  5. Use the table below to discover your ring size.

MEASURE YOUR CURRENT RING

  1. Select a ring that properly fits the intended finger.
  2. Place the ring over the circles below, matching the inside edge of the ring to the circle nearest in size. This measurement refers to the inside diameter of the ring.
  3. If the ring falls between two sizes, order the larger size.
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Country Availability

Free shipping and country tax is absorbed in these countries
Singapore, United States*, United Kingdom
*State tax may apply in certain states in the US
Free shipping and taxes are charged in these countries
Albania, Andorra, Armenia, Austria, Belarus, Bosnia & Herzegovina, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Georgia, Germany, Gibraltar, Greece, Greenland, Guernsey, Hungary, Iceland, Ireland, Isle of Man, Jersey, Kosovo, Latvia, Liechtenstein, Lithuania, Malta, Monaco, Montenegro, North Macedonia, Norway, Poland, Portugal, Romania, San Marino, Serbia, Slovakia, Slovenia, Sweden, Turkey, Ukraine, Morocco
Delivery fees are charged in these countries
Brunei, Cambodia, Israel, Maldives, Mauritius, Mongolia, Myanmar (Burma), Pakistan, South Korea, Sri Lanka, Bangladesh, Egypt, India, Iraq, Laos, Madagascar, Ghana, Guinea, Kenya, New Zealand, Nigeria, Oman, Qatar, Senegal, South Sudan, Sudan, Taiwan, Togo, Tunisia, Uganda, Djibouti, Ethiopia, Liberia, Libya, Malawi, Mali, Sierra Leone, Zimbabwe, Tanzania, Yemen, Western Sahara, Cayman Islands, Dominican Republic, Ecuador, Paraguay, Trinidad & Tobago, Argentina, Brazil, Chile, Colombia, Costa Rica, El Salvador, Bolivia, British Virgin Islands, Guatemala, Jamaica, St. Kitts & Nevis, St. Lucia, Peru, Venezuela, Barbados, Bermuda, Curaçao, Mexico, Panama

If your country does not appear on our list provided above, please select your country below to view the availability list:

Select your country

For all other countries, please email us at customerservice@calecim.com

Delivery Information

Order
Delivery Time
Orders within USA
3 to 6 working days
Orders within UK
3 to 6 working days
Orders within Singapore*
2 working days
International Shipping
Up to 14 working days
 
 

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Professional Serum 5ml
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ARE YOU A PROFESSIONAL?
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Add to cart  —  £80.00 GBP
Professional Serum 5ml
Professional Serum 5ml
Professional Serum 5ml

WHAT IT IS

Pure, Potent, Powerful

Our Professional Serum contains the highest concentration of PTT-6® A few drops transforms your daily skincare, turning it into a regenerative experience for your skin.

EVIDENCE BASED SKINCARE 1

56%

increase in elastin production

83%

increase in hyaluronic acid production

6x

increase in skin density

Professional Serum 5ml

Volume: 1 x 5ml £80.00 GBP

  • Contains the highest concentration of PTT-6®
  • Keeps skin supple and healthy while targeting fine lines, wrinkles, and hyperpigmentation
  • Can be used with other skincare daily to optimize results
  • Recommended for clinical or at-home skin treatments to boost skin repair and renewal

skin repair

Skin repairing

Helps calm inflammation

How Auto-Replenish works

  • Save 20% on most CALECIM® Professional products
  • Easily pause or cancel your plan (after a minimum of 3 delivery cycles)
  • Adjust order frequency anytime, receive what you need when you need it
  • Earn loyalty points on your Auto-replenish orders, to be redeemed on site
  • Free delivery in US, UK and EU
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Sorry, we are not able to deliver to your country. Please contact us at dermaesthetic@menariniapac.com to request for more information about clinics selling CALECIM® Professional products in your area.

FREE Professional Serum or Multi-Action Cream with skincare purchase above .

No limit to number of free gifts.
Limited period. Act Now.

Receive FREE Restorative Hydration Cream 20ml with every purchase above .
Save $114 with your next order.
No limits to free gifts.

Select Type:

1 x 5ml
2 x 5ml
6 x 5ml
One-time
£80.00 GBP
Delivery every 2 Weeks

Inclusive of VAT

Pay in 3 interest-free instalments with SplitIt

Free express delivery
Complimentary samples
Who it's for? How to use Ingredient List

All skin types, mature skin, post-procedure recovery

Three ways of using the Professional Serum

  1. At home as part of your anti-aging skincare
    Apply one pipette to the entire face before other creams and treatments
  2. At home after a microneedling / chemical peel / dermabrasion session
    Transform your at home procedure to clinical grade with a few pipettes of Professional Serum
  3. After any clinical skin treatment
    Widely used by clinics to reduce downtime, procedure discomfort and swelling, as well as optimize aesthetic outcomes

Active Ingredients
PTT-6®: (Stem cell derived Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid)

Show full ingredients
More about active ingredients

Full ingredient list
Aqua, Hyaluronic Acid, Glycoproteins, 1,2-Hexanediol, Soluble Collagens, Albumin, Fibronectins.

Show active ingredients
About this product Why pink?Before & After

Before

After

After 3 micro needling sessions with the Professional Serum. Conducted by Wendy Hurn at Embrace Medical Aesthetics.

Before

After

Plasma shower treatment with Professional Serum infusion. Conducted by Dr B. Molina, Medikas

Before

After

12 week treatment of acne and acne scarring using topical treatments, microneedling and Professional Serum. Conducted by Adrian Baker of Lumiere MediSpa #2

Before

After

4 sessions of Nano-fractional radio frequency treatment with application of Professional Serum, over 12 weeks. Conducted by Dr R. Pamela, CELV Clinic

Before

After

4 sessions of Nano-fractional radio frequency treatment with application of Professional Serum, over 12 weeks. Conducted by Dr R. Pamela, CELV Clinic

Before

After

Split-face trial with Professional Serum applied on one side of face post ablative laser procedure. Conducted by Dr D Kim, Orange County Plastic Surgery

Before

After

Professional Serum applied on right side post ablative laser procedure. Conducted by Dr D Kim, Orange County Plastic Surgery

WHAT IT IS

Pure, Potent, Powerful

Our Professional Serum contains the highest concentration of PTT-6® A few drops transforms your daily skincare, turning it into a regenerative experience for your skin.

BENEFITS

We do what other
skincare can’t

Penetrates the deepest layers of the skin to rejuvenate from the inside out. PTT-6® has been proven to reduce fine lines and wrinkles, improve skin texture and elasticity and promote skin healing.

EVIDENCE BASED SKINCARE 1

56%

increase in elastin production

83%

increase in hyaluronic acid production

6x

increase in skin density

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WHY IS THE PROFESSIONAL SERUM PINK?

We use a pink pH indicator to monitor the state of active growth factors and proteins within the Professional Serum. Because of its high concentration of biologically-derived active ingredient, it is important that the conditions remain optimal for these active factors to thrive.

Do not use the Serum if it has discolored, and contact our customer service

KEY INGREDIENTS
PTT-6®
Growth Factors
Exosomes
Albumin
Fibronectins
PTT-6® harnesses the body's natural mechanisms of regeneration. It contains over 3,000 proteins, including growth factors, cytokines and exosomes that signal cells to regenerate.
Naturally occurring proteins that are produced by cells in your body, such as skin cells, fat cells or stem cells. Their role is to stimulate growth, healing and regeneration in living tissues. Depending on its type and source, growth factors can boost collagen synthesis, prompt cells to produce components that improve skin firmness and elasticity, strengthen the skin barrier and repair and rejuvenate skin.
Found in all mammalian cells, exosomes are nano-sized extracellular vesicles that are released from cells . Exosomes contain proteins and growth factors that are important in helping one cell communicate with another to promote healing.
A protein that maintains osmotic (water) pressure within the skin's cells. It is required for skin turgor, helping to maintain a plump and youthful complexion.
One of the gkycoproteins in PTT-6® that helps repair skin and build collagen by providing the binding element required for these processes to take place. It strengthens, hydrates and protects skin cells.

TRUSTED BY DOCTORS

“The powers of the growth factors and exosomes in CALECIM® Professional have transformed our post-procedure results and patient’s recovery, making treatments a far more pleasant experience for them.”

Dr. Carlos Escobar

Medical Director of The Axis Clinic

Find a CALECIM® clinic close to you

USER REVIEWS

Reviews from

More reviews
star star star star star

“I look like I’ve had a face lift”

This is the most amazing serum and it takes about two weeks to really start seeing significant lifting and smoothing of your skin. I’m on my second 5ml bottle and I look like I’ve had a face lift. Amazing results. It soaks in to your skin immediately and feels wonderful!

Jennifer Cuddy

star star star star star

“Love this product after fraxel”

I used the calecim professional serum which is super expensive, but it’s really worth every penny. After fraxel I usually swell up and bruise. Neither occurs with the serum. No bruises or swelling

Karen Korcheck

star star star star star

“This serum, while pricey, is worth every penny”

This serum adds a glow, diminishes fine lines and wrinkles, and fills out my skin’s volume like nothing else. An essential part of a daily routine!

Robin Gregg

star star star star star

“Helps with healing”

I love using the serum after a microneedling session because it does help with healing

Michelle

More reviews

FREQUENT QUESTIONS

If you have any other enquiries, please leave us a message on our chat. We will get back to you within 2 working days.
Other questions
Which product do I choose to use post-procedure: Professional Serum or Recovery Night Complex?
The Professional Serum is designed to be used after in-clinic procedures. It is light and easily absorbed into the skin with a pH that is designed to be gentle on sensitized skin.

The Recovery Night Complex can also be used on sensitized skin, but it is better applied at night because of its gel like texture that forms alight film over the skin to protect and hydrate it. This texture is also not conducive to the convenient application of sunblock or makeup which is why it is not recommended for use in the day.

As a night-time regimen on the day of the procedure, you can apply the Professional Serum followed by the Recovery Night Complex.
Why is the Professional Serum pink?
Professional Serum contains phenolsulfonphthalein (a pH indicator) which is reddish/dark pink. As each batch of protein mix may have slight differences in acidity or alkalinity, the color can range from light yellow/orange to light red/dark pink. This is within our acceptable range.

We use the pH indicator to monitor the state of the active ingredient. As it is derived from an organic source and is high in biological matter, it may be prone to bacteria contamination. The pH indicator uses the acidity level within the formula to assess the health of the active proteins and growth factors within.

It is recommended to keep CALECIM® Professional products in cool conditions, not exceeding 33°C or 91.4°F. Please discontinue usage of the product if the color appears to be different from the stated acceptable range and contact us at customerservice@calecim.com
Why is there a smell to the Professional Serum?
The Professional Serum is fragrance-free. The smell comes from the high concentration of active ingredient, mainly Cord Lining extract, in the formulation. The smell disappears soon after application and most users don’t notice it after a few minutes.
Why does my ampoule of Professional Serum look and smell different from the last one?
The extract derived from each batch of Cord Lining is slightly different. This results in slight differences in color and smell in the end product because of the high concentration of active ingredient used.
When can I start seeing results from the Professional Serum?
When Professional Serum is used after in-clinic procedures, the calming and soothing effect is usually quite rapid with patients experiencing some amounts of decreased redness, swelling and discomfort within 15 minutes of application.
Can I use CALECIM® Professional with types of Vitamin C, AHAs, BHAs and anti-oxidants? How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?
CALECIM® Professional works well with most active ingredients commonly used in other skincare. Your skincare should be layered according to the viscosity of the product. Water-based products should be applied first (like toners, and watery serums), followed by gel-like textures. Light creams can be applied after, followed by heavier creams. For AM regimens, sunblock should be applied last.
Is this safe to use immediately after a skin procedure?
It depends on how ablative your procedure was. All creams / serums / gels should only be applied to skin that has fully epithelized.
Can I use CALECIM® Professional products if I have acne?
While the occasional pimple may be part of the natural process of skin renewal, you should avoid the use any CALECIM® Professional skincare if you have active acne. Your doctor or dermatologist will be able to ascertain whether you are a suitable candidate for the product.
Can I use CALECIM® Professional products if I am breast-feeding or pregnant?
Yes, CALECIM® Professional products are safe for those who are pregnant or breastfeeding. However, we highly recommend that you consult your obstetrician/gynaecologist before starting any new skincare routine.
Is CALECIM® Professional approved by the USFDA?
Cosmetic products such as CALECIM® Professional do not require the approval of the USFDA to enter a market. The cosmetic industry is however regulated by the USFDA through its VCRP program. CALECIM® Professional and all its products are registered with the USFDA VCRP.
Active Ingredients
Cord Lining Conditioned Media (Stem cell derived Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid)
Show More
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1 Results derived from in-vitro tests to determine the effects of PTT-6® on enhancement on skin proliferation, skin density, hyaluronic and elastin expression, using cell-based assay models of human keratinocytes and fibroblasts. Study conducted and designed by CellResearchCorp labs.
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