Learn>Explore by Concern>Menopause Hair Loss>What Is PTT-6®?

What Is PTT-6®?

PTT-6® is CALECIM’s patented technology containing a proprietary blend of growth factors, cytokines and exosomal proteins derived from ethically sourced umbilical cord lining stem cell research. Unlike single-ingredient approaches, PTT-6® contains a broad profile of signaling molecules that work together to support communication within the scalp environment.

Developed from regenerative medicine research, PTT-6® contains more than 3,000 naturally occurring proteins involved in cellular communication. These include growth factors, cytokines and exosomal proteins that help facilitate biological signalling within the scalp and hair follicle environment.

Hair follicles are highly active structures that depend on constant communication between surrounding cells throughout the hair growth cycle. As we age, and particularly during periods of hormonal change such as menopause, the environment surrounding the follicle may become less supportive of healthy hair growth. Technologies such as PTT-6® are designed to provide biologically active signalling molecules that help support the scalp environment and healthier-looking hair growth.

Today, PTT-6® is incorporated into professional and at-home hair restoration protocols and is used by clinicians, trichologists and consumers as part of comprehensive programmes designed to support scalp health, hair quality and overall hair appearance.

Clinical Perspective

PTT-6® has been evaluated in women experiencing menopausal and androgenetic hair loss, with findings published in the peer-reviewed PMFA Journal (Plastic, Maxillofacial and Aesthetic Journal). In the published evaluation, women using a PTT-6®-based hair restoration protocol demonstrated improvements in hair appearance, density and overall hair quality over a 12-week period.

Your Questions Answered

General guidance to help you understand common hair-change experiences. It is not a substitute for medical advice.
What Are The Early Signs Of Menopause Hair Loss?

Common signs include:

  • Increased shedding
  • Reduced volume
  • A widening centre part
  • Increased scalp visibility
  • Reduced ponytail thickness
  • Slower regrowth
  • Finer hair texture

Many women begin noticing these changes during perimenopause, before menopause itself.

What Vitamins And Nutrients Affect Hair Growth?

Hair growth may be affected by:

While supplements can be helpful when a deficiency is identified, more is not always better. Hair follicles require adequate protein, iron, vitamin D, vitamin B12, folate and zinc to support normal growth. For many menopausal women, low ferritin (iron stores) and vitamin D insufficiency are among the most commonly identified findings. A balanced diet, appropriate testing and targeted supplementation where required are generally more effective than taking multiple hair supplements without identifying an underlying deficiency.

  • Protein intake
  • Iron status
  • Vitamin D
  • Vitamin B12
  • Zinc
  • Thyroid health

Women concerned about hair loss should discuss appropriate testing with a healthcare professional.

Can Menopausal Hair Loss Grow Back?

The answer depends on the underlying cause.

Temporary shedding may improve once the trigger is addressed. Where follicle miniaturization has occurred, earlier intervention is often associated with better outcomes.

Treatment approaches may include addressing nutritional deficiencies, supporting scalp health, managing underlying health conditions and using hair restoration therapies designed to support healthier-looking hair growth.

Because hair grows slowly, consistency is important and visible improvements typically require several months.

Is It Too Late To Regrow Hair After Menopause?

Earlier intervention is generally associated with better outcomes, but many women still see meaningful improvements even after years of thinning. Hair follicles often exist on a spectrum between healthy growth and complete inactivity. Where follicles remain viable, supporting scalp health, addressing nutritional deficiencies and using targeted hair restoration approaches may help improve hair appearance, density and quality over time. The goal is not simply regrowth, but helping existing follicles perform at their best.