Corrective treatment for skin
showing signs of aging
Multi Action Cream Starter Size 20g reward
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I have had rosacea since my menopause years started and I could not go for my facials and lasers. However, CALECIM® products have greatly helped to maintain my skin.
After only two weeks I and my clients have displayed significant and noticeable improvements in sagging skin, wrinkles and texture of the skin! This product performs!
This one is the real deal. I have used it for a year, and I can tell by how I look through Zoom. My face is greatly rejuvenated and lifted.
Stem Cell Signaling
Leads to Aging Skin
Protein signals generated by stem cells are important as they actively repair and regenerate the skin.
As we age, the number of working stem cell falls, and the quantity of rejuvenating proteins they secrete is decreased.
Signs of Aging
- Decrease skin fullness (thickness) due to decreased production of extracellular matrix proteins: Facial shape and contours change
- Decreased skin elasticity due to decreased elastin production: Skin begins to sag
- Slowing down of epidermal cell turnover: Skin becomes crepey and discoloured with uneven pigmentation.
Powerful Growth Factors and Proteins are
“Youth Messages” to the Skin
Multi-Action Cream directs “Youth Messages” derived from patented cord lining extract to activate the cells in your skin responsible for hydrating and firming.
skin cell proliferation
Evidence of Increased Dermal and Epidermal Fullness
In-vitro tests using a 3-dimensional skin equivalent
to assess skin density reveal:
Exposure to Cord Lining Conditioned Media increased cell proliferation, resulting in increased epidermal and dermal thickness of between 500% to 700%
Immunohistochemistry staining for Elastin
In-vitro tests using human dermal fibroblasts
To compare effects of human dermal fibroblasts with Cord Lining Conditioned Media
Using a series of optical density images
Showed that CLCM upregulated expression of Elastin by 56%
Evidence of Increased Epidermal Proliferation
In-vitro tests using aged skin keratinocytes
and fibroblasts reveal:
A significant increase in epidermal cell proliferation was observed
from Day 6 onwards after exposure to
Cord Lining Conditioned Media.
Created by Scientists
“I have observed increased skin fullness resulting in a lifting effect, a tighter jawline, elevated eyebrows, and enhanced facial definition.”
Dr. Ziv Peled
San Francisco, USA
“Red deer umbilical cord lining mesenchymal stem cell extract was effective in rejuvenating the aging face.”
Dr. Mitchel Goldman
Double Board-certified Cosmetic Dermatologist,
San Diego, California, USA
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The 14-day difference with
Our active ingredient, Rejuvenating Conditioned Media, is not just studied and vigorously tested in the lab.
Its results on real patients speak for themselves.
How to Use
- Cleanse and tone skin
- Apply a small amount to all facial zones, extending past the jawline to the neck. Gently smooth the cream in.
- Use on its own, or below your regular moisturizer or Restorative Hydration Cream, depending on skin type. Dry skin types may require additional moisturizer. Use AM and PM.