Aging skin is a sign of low stem cell count. Why you need to replenish stem cell signals

Stem cells are the basic building blocks of the body that can become any other type of cell. They are also responsible for the renewal and repair work in all parts of your body, including your skin. Stem cells are thus essential in keeping your body and skin youthful and healthy. Ageing takes place when the quantity and quality of stem cells diminish as we get older. This leads to your body’s weakened ability to combat the daily ravages of the environment and resist the effects of gravity on your skin. Skin that is not able to produce enough glycoproteins, such as hyaluronic acid and elastin at the dermal layer starts to sag. Skin function suffers when stem cells are no longer sending messages to the epidermal layer to renew itself; this leads to a dry, crepey surface that accumulates pigmentation.

Stem cell skincare: Recharging skin with powerful growth factors and exosomes

CALECIM® Professional is the world’s only skincare that is powered by stem cells from the umbilical cord lining. Proteins, comprised of powerful growth factors and exosomes, are secreted from this patented source of stem cells, and make up the active ingredient, PTT-6,®  in the range of CALECIM® Professional cosmeceuticals.

Let’s take a look at why CALECIM® Professional’s source of stem cells is so unique and relevant to skin revitalization, and how its active ingredients can help maintain your skin’s tightness, elasticity, radiance, and overall health.

Umbilical Cord Lining Produces Two Types of Stem Cells

There are two types of stem cells in the lining membrane of the umbilical cord, which can potentially differentiate into many different cells:

  • Epithelial stem cells — are able to morph into surface lining cells, such as the epidermal layer of the skin.
  • Mesenchymal stem cells — can differentiate into structural cells such as your inner organs, nerve, fat, or cartilage, as well as the dermal layer of skin.

Because of their ability to constitute the entire structure of the skin, from the dermis to epidermis, mesenchymal and epithelial stem cells are your essential tools in renewing and repairing your skin, helping keep aging at bay. Stem cells do their work by sending out exosomes that communicate with skin cells. These proteins act as messages that regulate skin function, signalling old skin cells to shed, and new cells to proliferate. Stem cells are also the command centre for action when a wound or traumatic injury is sustained; sending out messages for surrounding skin cells to move towards one another to close the wound, and encouraging the production of new skin cells.

Defying ageing with stem cell messages

When you are young, the young stem cells within you are extremely efficient and vigorous in producing and sending messages to your skin, encouraging it to renew itself regularly. In young and healthy skin, complete epidermal cell turnover takes place every 28 days. With ageing, stem cell signals drop, which leads to a sluggish skin cell turnover. It is not uncommon for aged skin epidermal cell turnover to slow to 40 days or more. Old skin cells that remain on the surface of your skin lose their water retention ability and start to accumulate pigment. The result is a crepey, dry and rough surface with discoloration. 

Reduced stem cell signalling also means that the dermal layers are affected with reduced production of all the glycoproteins that are needed for your skin to retain moisture, and elastin to defy gravity.

What is lost from your dermal layers are:

  • Skin-strengthening collagen that provides skin with shape and volume
  • Elastin that provides skin with pliability and resilience
  • Skin-hydrating hyaluronic acid that allows skin to hold on to moisture so that it is plump and radiant
Clinical skincare recommended by dermatologists

For the consistent and healthy renewal of cells that are crucial to maintaining your skin's radiance, smoothness, and firmness, CALECIM® Professional delivers the active ingredient that can accelerate the skin’s cellular revitalization.

The proprietary formula in each of CALECIM®Professional’s rejuvenative creams is derived from stem cell extract from cord lining stem cells. These growth factors and exosomes help

  • Enhance skin shape
  • Restore skin volume
  • Improve skin resiliency
  • Increase skin moisture
  • Minimize facial lines and wrinkles

CALECIM® Professional treatment creams are rich in stem cell growth factors and exosomes that promote regular cycles of cell production and cell shedding, as well as to encourage glycoprotein production, to notably renew, revive and restore skin in as little as two weeks.

PTT-6®  provides epidermal growth factors and other powerful exosomes that target skin ageing 

The unique blend of growth factors and exosomes produced by the stem cells from cord lining is rich in the following ingredients:

  • Essential Proteins and growth factors such as Epidermal growth factors which are responsible for sending out the signals that regulate skin function
  • Collagen to strengthen and contour the skin
  • Collagen-supporting fibronectin
  • Hyaluronic acid to hydrate and volumize the skin

With our powerful range of skin creams and serums, you can help reverse signs of ageing by targeting the root cause using stem cell-derived growth factors and exosomes. 

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