Corrective treatment for skin
showing signs of aging

Test US/UK MAC

  • Works to improve signs of skin laxity, loss of facial contours, and diminished skin fullness
  • Visibly smoothens deep wrinkles and facial creases
  • Enhances skin health and resilience
  • ✓ Free express delivery in 3 working days
  • ✓ Free samples with every purchase

Produced in a
Stem Cell Lab

Globally
Patented

Trusted by
Doctors

Ethically
Derived

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Decreased Stem Cell Signaling Leads to Aging Skin

Decreased
Stem Cell Signaling
Leads to Aging Skin

Protein signals generated by stem cells are important as they actively repair and regenerate the skin.

As we age, the number of working stem cell falls, and the quantity of rejuvenating proteins they secrete is decreased.

Powerful Growth Factors and Proteins are
“Youth Messages” to the Skin

Multi-Action Cream directs “Youth Messages” derived from patented cord lining extract to activate the cells in your skin responsible for hydrating and firming.

600%

Increase in
skin density

56%

Increase in
elastin expression

42%

Increase in
skin cell proliferation

Results from in-vitro tests using Cord Lining Conditioned Media
and aged keratinocytes and fibroblasts.

More on Our Science

Created by Scientists

Dr. Ziv Peled

“I have observed increased skin fullness resulting in a lifting effect, a tighter jawline, elevated eyebrows, and enhanced facial definition.”

TRUSTED BY

Dr. Ziv Peled

Plastic Surgeon,
San Francisco, USA

See Clinical Observation by Dr. Ziv Peled
Dr. Mitchel Goldman

“Red deer umbilical cord lining mesenchymal stem cell extract was effective in rejuvenating the aging face.”

TRUSTED BY

Dr. Mitchel Goldman

Double Board-certified Cosmetic Dermatologist,
San Diego, California, USA

Read Full Abstract
Before using MAC - Image 1 After using MAC - Image 1

Clinical observation by Dr Ziv Peled, Peled Surgery

Before using MAC - Image 3 After using MAC - Image 3

Clinical observation by Dr Ziv Peled, Peled Surgery

Before using MAC - Image 5 After using MAC - Image 5

Clinical observation by Dr Ziv Peled, Peled Surgery

The 14-day difference with
Multi-Action Cream

Clinically Validated
by Patients

Our active ingredient, Rejuvenating Conditioned Media, is not just studied and vigorously tested in the lab.

Its results on real patients speak for themselves.

How to Use

  • Cleanse and tone skin
  • Apply a small amount to all facial zones, extending past the jawline to the neck. Gently smooth the cream in.
  • Use on its own, or below your regular moisturizer or Restorative Hydration Cream, depending on skin type. Dry skin types may require additional moisturizer. Use AM and PM.

Use Together

Powerful Alone.
Transformative Together.

Multi-Action Cream +
Restorative Hydration Cream

Multi-Action Cream
Restorative Hydration Cream

Try the power duo now in starter sizes:

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More Questions

Why is there a smell to the Multi-Action Cream?

The Multi-Action Cream is fragrance-free. The smell comes from the high concentration of active ingredient, mainly Cord Lining extract, in the formulation. The smell disappears soon after application and most users don’t notice it after a few minutes.

Which cream is more suitable for my skintype: the Multi-Action Cream or Restorative Hydration Cream?

Multi-Action Cream is designed for patients who are looking for a powerful anti-aging corrective treatment. It targets significant signs of aging such as skin laxity, deep wrinkles and folds, and loss of skin density.

Restorative Hydration Cream is for all skin types that will benefit from deep hydration. It restores radiance to dehydrated skins, smoothing out fine line and shadows.

These two products can be used together. With the Multi-Action Cream being applied before the Restorative Hydration Cream.

Why does my current jar of Multi-Action Cream look and smell different from the last one?

The extract derived from each batch of Cord Lining is slightly different. This results in slight differences in color and smell in the end product because of the high concentration of active ingredient used.

When can I start seeing results from the Multi-Action Cream?

When used as a daily moisturizer or corrective treatment, Multi-Action Cream supplies the skin nutrients that aids and boosts the restoration of your skin’s renewal cycle back to 28 days. This process is known as the skin-cycle reset and may take two to four weeks for results to take effect. Optimal results can usually be observed after 90 days.

Can I use this as a moisturizer?

It depends on your skin type. If your skin is Oily / Normal / Combination, you may find the Multi-Action Cream sufficiently emollient for your skin. If your skin is very dry, you may want to apply a separate moisturizer above, or pair it with the Restorative Hydration Cream.

Can I use CALECIM® Professional with Retin-A, types of Retinols, types of Vitamin C, AHAs, BHAs and anti-oxidants?
How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?

CALECIM® Professional works well with most active ingredients commonly used in other skincare. Your skincare should be layered according to the viscosity of the product. Water-based products should be applied first (like toners, and watery serums), followed by gel-like textures. Light creams can be applied after, followed by heavier creams. For AM regimens, sunblock should be applied last.

Is this safe to use immediately after a skin procedure?

It depends on how ablative your procedure was. All creams / serums / gels should only be applied to skin that has fully epithelized.

Can I use CALECIM® Professional products if I have acne?

While the occasional pimple may be part of the natural process of skin renewal, you should avoid the use any CALECIM® Professional skincare if you have active acne. Your doctor or dermatologist will be able to ascertain whether you are a suitable candidate for the product.

Can I use CALECIM® Professional products if I am breast-feeding or pregnant?

Yes, CALECIM® Professional products are safe for those who are pregnant or breastfeeding. However, we highly recommend that you consult your obstetrician/gynaecologist before starting any new skincare routine.

Active Ingredients

Cord Lining Conditioned Media (Stem cell derived Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid), Tocopherol, Potassium Lactate, Fatty Acids (Oleic Acid, Linoleic acid, Palmitic acid, Stearic acid), Glyceryl Stearate