
Years of Research
- Obstructs melanin transfer
- Reduces free radicals
- Accelerates the body's natural autophagy, which rids unwanted tissue like melanin
Two Novel Ingredients
Several Proven Technologies
- Strengthens the skin’s reaction to inflammation, the key cause of skin discoloration
- Inhibits Tyrosinase, the catalyst for melanin
- Improves the skin’s repair mechanisms

This combination treats the entire process of hyperpigmentation and melasma, not only after hyper-melanosis takes place but well before.
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4 weeks usage of
Professional Pigment Solution
Clinically Validated
by Patients
Our active ingredient is not just studied and vigorously tested in the lab.
Its results on real patients speak for themselves.
How to Use
- Cleanse and tone skin
- Apply a small amount to affected areas. One pump of product is sufficient for one facial zone eg. One side of the cheek area.
- If you are applying the Pigment Solution to all facial regions, you can target treat stubborn or particularly darkened areas with an extra layer of Pigment Solution.
- Apply other corrective treatment serums / creams, and moisturizers above.
- Use AM and PM. Use sunblock liberally AM, and reapply every 3 hours when in direct contact to sunlight or water.


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More Questions
When can I start seeing results from the Professional Pigment Solution?
When can I start seeing results from the Professional Pigment Solution?
In internal observations, patients have started seeing some improvement in skin tone in about 3 weeks. Optimal results can usually be observed after 90 days.
Can I use CALECIM® Professional with types of Vitamin C, AHAs, BHAs and anti-oxidants?
How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?
Can I use CALECIM® Professional with types of Vitamin C, AHAs, BHAs and anti-oxidants?
How do I incorporate CALECIM® Professional into my regimen with these other active ingredients?
CALECIM® Professional works well with most active ingredients commonly used in other skincare. Your skincare should be layered according to the viscosity of the product. Water-based products should be applied first (like toners, and watery serums), followed by gel-like textures. Light creams can be applied after, followed by heavier creams. For AM regimens, sunblock should be applied last.
Is this safe to use immediately after a skin procedure?
Is this safe to use immediately after a skin procedure?
It depends on how ablative your procedure was. All creams / serums / gels should only be applied to skin that has fully epithelized.
Can I use CALECIM® Professional products if I have acne?
Can I use CALECIM® Professional products if I have acne?
While the occasional pimple may be part of the natural process of skin renewal, you should avoid the use any CALECIM® Professional skincare if you have active acne. Your doctor or dermatologist will be able to ascertain whether you are a suitable candidate for the product.
Can I use CALECIM® Professional products if I am breast-feeding or pregnant?
Can I use CALECIM® Professional products if I am breast-feeding or pregnant?
Yes, CALECIM® Professional products are safe for those who are pregnant or breastfeeding. However, we highly recommend that you consult your obstetrician/gynaecologist before starting any new skincare routine.
Is CALECIM® Professional approved by the USFDA?
Is CALECIM® Professional approved by the USFDA?
The cosmetic industry is regulated by the USFDA through its VCRP program. CALECIM® Professional and all its products are registered with the USFDA VCRP.
Active Ingredients
Active Ingredients
Rejuvenating Conditioned Media (Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid), 4-Butylresorcinol, Arbutin, Magnesium Ascorbyl Phosphate, Tranexamic Acid, Alpha-Arbutin, Glutathione, Arisaema Amurense Extract, Camellia Sinensis Leaf Extract, Sigesbeckia Orientalis Extract, Lactic Acid, Niacinamide, Cetearyl Isononanoate, Glycerin, Sorbitan Olivate, Tocopheryl Acetate, Allantoin, Lecithin, Linolenic Acid, Linoleic Acid, Ascorbyl Palmitate