When used with clinical procedures:
Apply to treatment area and press firmly into the skin with a gloved hand to ensure penetration. Use half to one full ampoule per treatment depending on area and degree of ablation.

When used at home:
Ensure skin is clean and free of any oily residue. A mild skin exfoliation before application might improve absorption of the product. Use one pipette full of Serum for the whole face. Apply a few drops on each facial zone and press into the skin. One ampoule holds approximately 10 pipettes of Serum.